Digital Pathophysiology Lab

The group is at the intersection of life and computational sciences, with a main focus on dynamic processes that evolve over time such as immune cell migration and progression of chronic diseases. We are distributed between the Theodore Kocher Institute of University of Bern (with the wet-lab experimental part), and the Euler instiute, USI Lugano (with a dry-lab computational part). The combination of both allows us to study complex spatiotemporal features in living organisms with the help of advanced time-lapse microscopy techniques and artificial intelligence.
We promote contamination between researchers from different fields and support Open Science practices - see IMMUNEMAP project link
Competences: time-lapse microscopy, bioimage analysis, computer vision, network theory, machine learning, trajectory mining, hardware prototyping, wearables and biosensors, amongst others.
WEBSITE UNDER COSTRUCTION

Newsflash

internship extravolt

[CLOSED] INTERNSHIP OFFER (PAID)

We are looking for a research assistant willing to engage in an interdisciplinary project art the forefront of immunology, imaging, and engineering to modulate the extravasation of inflammatory cells through the blood brain barrier (BBB) using electric stimulation.

More info here https://www.linkedin.com/posts/diego-ulisse-pizzagalli-83254a28_internship-offer-activity-7267968831199858688-a9ld?utm_source=share&utm_medium=member_desktop

Our competences

Bioimaging
We develop and apply image analysis methods to extract novel insights from biomedical imaging data.
Trajectory analysis
We use time-series to model dynamic processes evolving over time, including cell behavior, and disease dynamics.
Cell migration
We employ in vtro models to study cell behavior via time-lapse microscopy and collaborate with partners from the immunemap network performing intravital imaging studies
Hardware and Software
We develop hardware prototypes and software for specific biomedical applications. This includes PCB design and assembly, firmware and software development.